Over the decades many orders of religious were in residence at St. Joseph. These included :The Sisters of Mercy, the Sisters of the Blessed Sacrament, the Sisters of the Most Blessed Trinity, the Carmelites, Benedictines, and Missionary Sisters of the Most Blessed Trinity. These will be individually profiled in upcoming entries, as well as their role in Oklahoma history.
On August 1, 1912 a group of sisters arrived to prepare the facility to receive children. These included Sister Mary Scholastica (Superior), Sister Mary Anthony, Sister Mary Raphael, Sister Mary Ambrose (Of the Sisters of Mercy in Oklahoma City).